Bioavailability and Pharmacokinetics of Oral Cocaine in Humans
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چکیده
منابع مشابه
Bioavailability and pharmacokinetics of oral meloxicam in llamas
BACKGROUND South American camelids in the United States have rapidly developed into an important agricultural industry in need of veterinary services. Pain management is challenging in camelids because there are no drugs currently approved by the U.S. Food and Drug Administration for use in these species. Dosage regimens used for many therapeutic drugs have been extrapolated from other ruminant...
متن کاملEnhancement of oral bioavailability of insulin in humans.
OBJECTIVE The purpose of this study is to investigate oral absorption of 1, 2 and 3 U/kg oral insulin five test products with different particle sizes in comparison with 0.1 U/kg subcutaneous reference formulation. METHODS Twenty five healthy volunteers participated in five studies using a two-phase, two-sequence crossover design with washout period of one day. Mean disposition kinetics was d...
متن کاملepidemiological study of oral and pharyngeal cancers in kermanshah province from march 1993 to march 2006
چکیده ندارد.
15 صفحه اولPharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans
BACKGROUND The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice. METHODS We characterized the pharmacokinetic profile, pharmacokinetic-pharmacodynamic relationship, and urine recovery of lysergic acid diethylamide and its main metabolite after administration of a single oral...
متن کاملDifloxacin metabolism and pharmacokinetics in humans after single oral doses.
By using high-performance liquid chromatography, the metabolism and pharmacokinetics of difloxacin were characterized in humans after single oral doses of 200, 400, and 600 mg. Group mean peak levels in plasma were obtained 4 h after administration. The means of the individual peak levels for the 200-, 400-, and 600-mg groups were 2.17, 4.09, and 6.12 micrograms/ml, respectively. The mean respe...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2018
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/bky007